Neurofeedback vs TBI Case Study

Can Neurofeedback grow back brain matter in Moderate (unconscious) Traumatic Brain Injury Patients?

Case Study: Two Patients were treated with 20 sessions of QEEG guided neurofeedback therapy.

Patient 1: Twenty year old male with history of road traffic accident (RTA) presented with the loss of consciousness lasting approximately one hour and had left ear bleed.
Patient 2: Patient 2: Twelve year old female with history of RTA presented with loss of consciousness (LOC) for approximately one week with both ears bleed and traumatic amnesia. CT scan had taken within 24 hours show features of diffuse axonal injury (DAI).

Results: During QEEG guided neurofeedback therapy the cognitive scores and concussion symptoms improved significantly (p<0.05). The QEEG guided neurofeedback therapy has shown significant increase in cortical grey matter (GM) volumes (p<0.0001) and fractional anisotropy (FA) of cortical white matter (WM) tracts (p<0.0001, voxel max 60 and above). There was a significant decrease in global, local efficiency, cost and Clustering coefficient of functional connectivity (Wilcoxon Sign Rank Test p<0.05). Interestingly there was a significant increase in thalamo-cortical connection (increase FA value) after QEEG guided neurofeedback therapy.
Conclusion: The QEEG guided neurofeedback therapy has shown significant changes in structural and functional connectivity among young moderately injured TBI patients.

If you have sustained a brain injury please contact your healthcare provider or contact Synapse Brain & Spine Center located in Lewes Delaware.