Average Improvement: 75-85%

Understanding Brain-Based Chronic Pain

Chronic pain is a complex and debilitating condition that affects millions of people worldwide. While many cases of chronic pain can be attributed to specific injuries or diseases, there’s a subset of chronic pain that is rooted in the brain itself. This type of pain, often referred to as brain-based chronic pain, presents unique challenges and requires a specialized approach to treatment and management.

The picture below is an example of a QEEG brain map of a Chronic Pain patient: 

(If you suspect you have brain based chronic pain please schedule your QEEG brain map today).

1. data show mostly changes of theta and beta oscillations in chronic pain, the latter particularly in frontal brain areas.

What is Brain-Based Chronic Pain?

Brain-based chronic pain, also known as central sensitization syndrome or centralized pain, occurs when the nervous system becomes hypersensitive and amplifies pain signals. Unlike acute pain, which serves as a warning sign of tissue damage or injury, chronic pain persists long after the initial injury has healed. In cases of brain-based chronic pain, the pain signals originate from the central nervous system itself, rather than from a specific injury or pathology.

Causes and Mechanisms

Several factors can contribute to the development of brain-based chronic pain, including:

  1. Neuroplasticity: The brain’s ability to reorganize and adapt in response to experiences and stimuli can lead to changes in pain processing pathways, resulting in heightened sensitivity to pain signals.

  2. Psychological Factors: Emotional stress, anxiety, depression, and trauma can all influence the perception of pain and contribute to the development of chronic pain conditions.

  3. Genetics: Genetic predispositions may make some individuals more susceptible to developing centralized pain syndromes.

  4. Persistent Inflammation: Chronic inflammation within the central nervous system can perpetuate pain signaling and contribute to the development of brain-based chronic pain.

Common Conditions Associated with Brain-Based Chronic Pain

Brain-based chronic pain can manifest in various forms, including:

  • Fibromyalgia: Characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and cognitive difficulties.

  • Chronic Headaches: Conditions such as migraines and tension-type headaches can be influenced by central sensitization mechanisms.

  • Complex Regional Pain Syndrome (CRPS): A chronic pain condition typically affecting one limb, often triggered by injury or trauma.

Treatment and Management Strategies

Managing brain-based chronic pain requires a multidisciplinary approach that addresses both the physical and psychological aspects of the condition. Treatment strategies may include:

  1. Neurofeedback therapy: Chronic pain is often associated with alterations in brain function, including abnormal patterns of brainwave activity. Neurofeedback therapy aims to address these abnormalities by promoting healthier brain functioning and reducing pain perception. Research suggests that neurofeedback may be particularly beneficial for individuals with brain-based chronic pain conditions, such as fibromyalgia, migraines, and neuropathic pain.

  2. Hyperbaric Oxygen Therapy: HBOT involves breathing oxygen in a pressurized environment, typically inside a chamber. The increased pressure allows the lungs to gather more oxygen than would be possible at normal air pressure. This oxygen-rich environment promotes the delivery of oxygen to tissues throughout the body, including areas with poor circulation or injury. Additionally, HBOT stimulates the release of growth factors and stem cells, aiding in tissue repair and regeneration.

  3. Laser Therapy: Laser therapy, also known as low-level laser therapy (LLLT) or cold laser therapy, is a non-invasive medical treatment that utilizes low-intensity laser light to stimulate healing and reduce pain and inflammation. 
  4. Mindfulness and Relaxation Techniques: Practices such as mindfulness meditation, deep breathing exercises, and progressive muscle relaxation can help reduce stress and promote relaxation, which may alleviate pain symptoms.

  5. Education and Self-Management: Learning about pain neuroscience and developing self-management strategies can empower individuals to better cope with their symptoms and improve their quality of life.

Other Conditions We Treat:

  1. OsteoarthritisOsteoarthritis is a degenerative joint disease that commonly affects the knees, hips, and hands. We offer a range of treatment options improve joint function, and slow down the progression of the disease.
  2. Rheumatoid Arthritis: Rheumatoid arthritis is an autoimmune condition that primarily affects the joints. Our comprehensive approach provides joint protection techniques, and physio therapy to reduce inflammation, alleviate pain, and prevent joint damage.
  3. Neck Pain: neck pain is a common orthopedic complaint that can originate from various causes, such as herniated discs, spinal stenosis, or muscle strain. Our multidisciplinary approach includes physiotherapy, chiropractic care, neurfeedback, lasers, and other integrative approaches. 
  4. Back Pain: Back pain is a common orthopedic complaint that can originate from various causes, such as herniated discs, spinal stenosis, or muscle strain. Our multidisciplinary offers a wide range of treatment options to relieve back pain and improve spinal health.
  5. Sports Injuries: Whether you’re a professional athlete or an active individual, sports injuries can significantly impact your performance and overall well-being. We offer specialized care for sports-related orthopedic injuries, including sprains, strains, fractures, and ligament tears. Our team focuses on a combination of rehabilitation. Our multidisciplinary offers a wide range of treatment options to alleviate many sports injuries. 
  6. Joint Injuries and Instability: Joint injuries, such as dislocations and ligament tears, can cause significant pain and instability. Our multidisciplinary offers a wide range of treatment options to relieve joint pain and improve stability. 


Brain-based chronic pain presents a significant challenge for both patients and healthcare providers due to its complex nature and multifaceted causes. By understanding the underlying mechanisms and employing a comprehensive treatment approach that addresses the physical, emotional, and cognitive aspects of pain, individuals with brain-based chronic pain can find relief and regain control over their lives. Early intervention, personalized treatment plans, and ongoing support are key to managing this chronic condition effectively. If you or someone you know is struggling with chronic pain, don’t hesitate to seek professional help and explore treatment options tailored to your needs.

At our Synapse Brain & Spine Center we specialize in the diagnosis, treatment, and management of various orthopedic conditions with a brain based approach.

Call today for orthopedic pain treatment in Lewes Delaware!